Major publications of the C.H.I.M.P.P. Group between 1989-1996 (May 4, 1996)

Research Articles
Huffman, M. A. and M. Seifu, 1989. Observations on the illness and consumption of a medicinal plant Vernonia amygdalina by a wild chimpanzee in the Mahale Mountains, Tanzania. Primates 30(1): 51-63.

Ohigashi, H., Takagaki, T., K. Koshimizu, T. Nishida, M.A.  Huffman, H. Takasaki, J. Jato, and D.N. Muanza, 1991.  Biological activities of plant extracts from tropical  Africa. African Study Monographs. 12(4): 201-210.

Ohigashi, H., M. Jisaka, T. Takagaki, H. Nozaki, T. Tada,  M.A. Huffman, T. Nishida, M. Kaji, and K. Koshimizu. 1991. A  bitter principle and a related steroid glucoside of Vernonia amygdalina, a possible medicinal plant for wild chimpanzees. Agricultural and Biological Chemistry. 55(4): 1201-1203.

Jisaka, M., M. Kawanaka, H. Sugiyama, K. Takegawa, M.A. Huffman, H. Ohigashi, and K. Koshimizu. 1992. Antischistosomal activities of sesquiterpene lactones and steroid glucosides from V. amygdalina, possibly used by wild chimpanzees against parasite-related disease. Bioscience, Biotechnology and Biochemistry.  56(5): 845-846.

Jisaka, M., H. Ohigashi, T. Takagaki, H. Nozaki, T. Tada, M. Hirota, R. Irie, M.A. Huffman, T. Nishida, M. Kaji, and K. Koshimizu. 1992. Bitter steroid glucosides,  Vernoniosides A1, A2 and A3 and related B1 from a possible medicinal plant Vernonia amygdalina, used by wild chimpanzees. Tetrahedron, 48:625-632.

Ohigashi, H.,  M. Jisaka, T. Takagaki, K. Koshimizu,  M.A. Huffman, T. Nishida, H. Takasaki,  and M. Kaji,  1992. Possible medicinal plants used by wild chimpanzees, and their physiologically active compounds.  Journal of African Studies. 39: 15-27. (in Japanese)

Huffman, M.A., S. Gotoh,  D. Izutsu, K. Koshimizu, M.S. Kalunde.  1993. Further observations on the use of the medicinal plant, Vernonia amygdalina (Del) by a wild chimpanzee, its possible affect on parasite load, and its phytochemistry.  African Study Monographs. 14(4): 227-240. 

Koshimizu, K., H. Ohigashi, M.A. Huffman, T. Nishida, H. Takasaki, 1993.  Physiological activities and the active constituents of possible medicinal plants Vernonia amygdalina,  Aspilia mossambicensis, and Ficus exasperata  used by wild chimpanzees of the Mahale Mountains, Tanzania. Int. J. Primatology .  14(2):345-356.

Jisaka, M.,  H. Ohigashi, K. Takegawa, M.A. Huffman, and K. Koshimizu. 1993. Antitumor and antimicrobial activities of bitter sesquiterpene lactones of Vernonia amygdalina, a possible medicinal plant used by wild chimpanzee. Bioscience, Biotechnology, Biochemistry. , 57(5): 833-834.

Jisaka, M.,  H. Ohigashi, H. Takegawa, M. Hirota, R. Irie, M.A. Huffman, K. Koshimizu., 1993.  Further steroid glucosides from  Vernonia amygdalina, a possible chimpanzee medicinal plant.  Phytochemistry. 34:409-413.

Ohigashi, H., M.A. Huffman, D. Izutsu, K. Koshimizu, M. Kawanaka, H. Sugiyama,  G.C. Kirby,  D.C. Warhurst, D. Allen, C.W. Wright, J.D. Phillipson, P. Timmon-David,  F. Delnas, R. Elias, G. Balansard.  1994. Toward the chemical ecology of medicinal plant-use in chimpanzees: The case of Vernonia amygdalina (Del.). A plant used by wild chimpanzees possibly for parasite-related diseases.  J. Chemical Ecology. 20(3): 541-553.

Kosimizu, K., Ohigashi, H., M.A. Huffman, 1994.  Use of Vernonia amygdalina by wild chimpanzees; Possible role of its bitter and related constituents. Physiology and Behavior. 57: 1209-1216. 

Mahaney, C.W., Hancock, R.G.V.,  Aufreiter, S., Huffman, M.A.  1996 Geochemistry and clay minerology of termite mound soil and a possible role of geophagy in chimpanzees of the Mahale Mountains, Tanzania.  Primates 37: 121-134

Huffman, M.A., Page, J.E., Sukhdeo, M.V.K.,  Gotoh, S.,  Kalunde, M.S., Chandrasiri, Towers, G.H.N.  in press. Leaf-swallowing by chimpanzees, a behavioral adaptation for the control of strongyle nematode infections.  Int. J. Primatol.

Book Chapters
Huffman, M.A. and R.W.  Wrangham, 1994.  Diversity of medicinal plant use by chimpanzees in the wild.  In: R.W. Wrangham, W.C. McGrew, F.B. deWall, P.G. Heltne Heltne (eds.)  Chimpanzee Cultures.  Harvard Univ. Press, Mass.  pp.  129-148

Huffman, M.A.,  Koshimizu, K, Ohigashi, H.  1996.  Ethnobotany and Zoopharmacognosy of Vernonia amygdalina (Del.).  A medicinal plant used by humans and wild chimpanzee.  In:  D.J.N. Hind (Editor-in-Chief). Proceedings of the Kew International Compositae Congress, 1994. Vol. 2. Biology & Utilization (vol. eds. P. Caligari & D.J.N. Hind), pp. 351-360, Royal Botanical Gardens Kew. 

Review Articles
Huffman, M.A., 1993.  An investigation of the use of medicinal plants by wild chimpanzees.  Current status and future prospects.  Primate Research 9:179-187.  (in Japanese with English Abstract)

Gasquet, M., Huffman, M.A., Wrangham, R.W. 1994. Les plantes medicinales utilises par les chimpanzes sauvages.  Metissages en Sante Animal (eds.) K. Kasonia & M. Ansay, Presses Universitaires de Namur, Namur (Belgium), pp. 289-297. (in french)

Huffman, M.A. 1995. La pharmacope des chimpanzes. La Recherche October Issue, pp. 66-71.(in french)

Other Articles
Huffman, M.A., 1990. Chimpanzees as doctors; Health maintenance behavior in chimpanzees.  Alumni Bulletin of the University of Osaka Dental School  63:  31-32. (in Japanese) 

Huffman, M.A., 1991. The use of naturally occurring plants for the possible treatment of parasite disease by wild chimpanzees.  In: Window on Wildlife, Research in Tanzania. E. Niemi & A. Outwater eds., Tanzania Printers,  Dar es Salaam pp 39-41.

Huffman, M.A.,  1994. The medicinal use of plants by chimpanzees.  In: Shokubutsu no Sekai. ("The world of plants" a weekly encyclopedic series on botany) Shukan Asahi Hyaka, Tokyo, May 29th issue,  p. 1-222 - 1-224. 
(in Japanese)

Wrangham, R. W., Huffman, M.A.,  Strier, K., Rodriguez, E., 1994. "Zoopharmcognisy: not too hard to swallow." The Sciences    

Huffman, M.A. , 1994. The C.H.I.M.P.P. Group: A multi-disciplinary investigation into the use of medicinal plants by chimpanzees.  Pan Africa News. 1(1): 3-5.